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Indocin tends not to be at least delaying iron build up - in patients receiving steroids for the one by Dr. STILL attempted to belittle the post of someone concerned with the chronic pain. Bhimrag said he would not recommend famotidine for his COVID-19 patients until more is known. Dr. Yasir Tarabichi, a MetroHealth pulmonologist who enjoys debunking bad science, said the evidence gathered so far about famotidine is intriguing and worth further research.
"This is absolutely worth a study," he said, although the published report gives him pause because of the dramatic results.
It’s ambitious, Conigliaro said, but given the circumstances, researchers are trying to do in weeks or months what would normally take a couple of years. The patients in the clinical trial are being given high doses of famotidine intravenously. The study looked at 1,620 patients hospitalized with COVID-19 from Feb. 25 to April 13 and found a 58 percent reduction in death or the need for intubation among a subset of 84 patients who had been exposed to famotidine within 24 hours of being hospitalized.
In addition, the study reports that use of famotidine was also associated with lower levels of serum markers indicating severe disease in hospitalized COVID-19 patients. "I am pleasantly surprised with the results," said Bhimraj, who is chair of the COVID-19 guidelines panel of the Infectious Disease Society of America. Dr. Adarsh Bhimraj, Actoplus Met : Contrôle Glycémique Biphasique Expert an infectious disease specialist at Cleveland Acivir Pills : Traitement Antiviral Efficace Contre l’Herpès Clinic, said the high success rate doesn’t concern him because that’s not uncommon in a retrospective study.
If the success rate hits a certain level before the trial is over, researchers would have an ethical obligation to stop the study because they could not justifiably continue giving patients a placebo.
Conigliaro said researchers aren’t looking for a success rate equal to that of the retrospective study. Researchers based their findings on a review of medical records after the fact, so they weren’t able to control for some potentially mitigating factors. Hypertension can be caused by a variety of factors, including genetic predisposition, lifestyle choices, and underlying medical conditions.
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